Pub. Date : 2012 Sep 25
PMID : 23158801
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | RESULTS: The mRNA expression of GR was 0.671 +- 0.002 in cigarette smoke exposure to asthmatic group and 0.595 +- 0.061 in SB203580 group (P = 0.065). | SB 203580 | nuclear receptor subfamily 3, group C, member 1 | Rattus norvegicus |
2 | The protein expression of GR was 0.700 +- 0.033 in cigarette smoke exposure to asthmatic group and 0.628 +- 0.091 in SB203580 group (P = 0.148). | SB 203580 | nuclear receptor subfamily 3, group C, member 1 | Rattus norvegicus |
3 | CONCLUSION: The mechanism of SB203580 enhancing the corticosteroid sensitivity may be improving nuclear translocation of GR to elevate corticosteroid sensitivity. | SB 203580 | nuclear receptor subfamily 3, group C, member 1 | Rattus norvegicus |