Title : A luminescent cyclometalated iridium(III) complex accumulates in mitochondria and induces mitochondrial shortening by conjugation to specific protein targets.

Pub. Date : 2012 Dec 21

PMID : 23148033






1 Functional Relationships(s)
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1 We report the cellular properties of a luminescent cyclometalated iridium(III) complex, [Ir(pq)(2)(phen-ITC)](PF(6)) (Ir-ITC; Hpq=2-phenylquinoline, phen-ITC=5-isothiocyanate-1,10-phenanthroline), that efficiently and specifically labels mitochondria in living mammalian cells. Iridium sperm associated antigen 17 Homo sapiens