Pub. Date : 2013 Sep 12
PMID : 23146902
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Serine-to-alanine mutations that blocked phosphorylation resulted in delayed recruitment of both NBN and ATM to DSBs. | dsbs | nibrin | Homo sapiens |
| 2 | The repair of DSBs in cells lacking full-length NBN was significantly delayed compared with control cells, whereas blocking phosphorylation of NBN resulted in a more modest delay in repair. | dsbs | nibrin | Homo sapiens |
| 3 | These data indicate that following the induction of DSBs, phosphorylation of NBN regulates its accumulation, and that of ATM, at sites of DNA DSB as well as the timing of the repair of these sites. | dsbs | nibrin | Homo sapiens |