Title : Effects of propylthiouracil on growth hormone and prolactin messenger ribonucleic acids in the rat pituitary.

Pub. Date : 1990 Mar

PMID : 2314053






3 Functional Relationships(s)
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1 The effects of hypothyroidism induced by propylthiouracil (PTU) treatment on growth hormone (GH) and prolactin (PRL) messenger ribonucleic acid (mRNA) levels were analyzed in adult female rat adenohypophyses by in situ hybridization histochemistry and Northern hybridization analyses. Propylthiouracil prolactin Rattus norvegicus
2 The effects of hypothyroidism induced by propylthiouracil (PTU) treatment on growth hormone (GH) and prolactin (PRL) messenger ribonucleic acid (mRNA) levels were analyzed in adult female rat adenohypophyses by in situ hybridization histochemistry and Northern hybridization analyses. Propylthiouracil prolactin Rattus norvegicus
3 Twenty-eight days of PTU treatment produced a significant decrease in GH mRNA levels and a smaller decrease in PRL mRNA determined by both in situ hybridization histochemistry and Northern hybridization analyses. Propylthiouracil prolactin Rattus norvegicus