Title : Glycine transporter type 1 occupancy by bitopertin: a positron emission tomography study in healthy volunteers.

Pub. Date : 2013 Feb

PMID : 23132267






3 Functional Relationships(s)
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Protein Name
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1 An approach for normalizing glutamate neurotransmission by enhancing NMDA receptor transmission is to increase glycine availability by inhibiting the glycine transporter type 1 (GlyT1). Glycine solute carrier family 6 member 9 Homo sapiens
2 An approach for normalizing glutamate neurotransmission by enhancing NMDA receptor transmission is to increase glycine availability by inhibiting the glycine transporter type 1 (GlyT1). Glycine solute carrier family 6 member 9 Homo sapiens
3 This study investigated the relationship between the plasma concentration of the glycine reuptake inhibitor bitopertin (RG1678) and brain GlyT1 occupancy. Glycine solute carrier family 6 member 9 Homo sapiens