Title : Effect of ovariectomy and treatment with ovarian steroids on vasopressin release and fluid balance in the rat.

Pub. Date : 1990 Feb

PMID : 2313218






3 Functional Relationships(s)
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1 Thus, of an initial group of rats given silicone elastomer implants containing 50, 500 or 1000 micrograms oestradiol in oil, plasma vasopressin concentrations were reduced after 7 days treatment with 1000 micrograms oestradiol implants in association with reduced plasma sodium concentrations. Estradiol arginine vasopressin Rattus norvegicus
2 Thus, of an initial group of rats given silicone elastomer implants containing 50, 500 or 1000 micrograms oestradiol in oil, plasma vasopressin concentrations were reduced after 7 days treatment with 1000 micrograms oestradiol implants in association with reduced plasma sodium concentrations. Estradiol arginine vasopressin Rattus norvegicus
3 However, after treatment for 14 days with implants containing only 50 micrograms oestradiol, plasma vasopressin concentrations were higher compared with the group receiving vehicle alone, despite the fact that the plasma osmolality was lower in the latter group, suggesting a long term resetting of the osmoreceptors. Estradiol arginine vasopressin Rattus norvegicus