Title : Effects of a cholecystokinin receptor antagonist on intestinal phase of pancreatic and biliary responses in man.

Pub. Date : 1990 Mar

PMID : 2312719






3 Functional Relationships(s)
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1 The present study was designed (a) to characterize the activity of loxiglumide as a peripheral cholecystokinin (CCK) antagonist in healthy human subjects, and (b) to determine whether CCK is a physiologic regulator of the intestinal phase of meal-stimulated exocrine pancreatic and biliary secretions in man. loxiglumide cholecystokinin Homo sapiens
2 The potency and selectivity of loxiglumide as an antagonist of CCK provides the tool for evaluating the role of CCK as a physiological mediator of meal-induced pancreatic and biliary responses in humans. loxiglumide cholecystokinin Homo sapiens
3 The potency and selectivity of loxiglumide as an antagonist of CCK provides the tool for evaluating the role of CCK as a physiological mediator of meal-induced pancreatic and biliary responses in humans. loxiglumide cholecystokinin Homo sapiens