Title : Molecular mechanisms of environmental organotin toxicity in mammals.

Pub. Date : 2012

PMID : 23123459






2 Functional Relationships(s)
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1 TBT and TPT are dual agonists of retinoid X receptor (RXR) and peroxisome proliferator-activated receptor gamma (PPARgamma); they also induce the differentiation of adipocytes in vitro and in vivo, probably through PPARgamma activation, suggesting that they may work as obesogens. tributyltin retinoid X receptor alpha Homo sapiens
2 TBT and TPT are dual agonists of retinoid X receptor (RXR) and peroxisome proliferator-activated receptor gamma (PPARgamma); they also induce the differentiation of adipocytes in vitro and in vivo, probably through PPARgamma activation, suggesting that they may work as obesogens. tributyltin retinoid X receptor alpha Homo sapiens