Title : Loss of O⁶-methylguanine-DNA methyltransferase confers collateral sensitivity to carmustine in topoisomerase II-mediated doxorubicin resistant triple negative breast cancer cells.

Pub. Date : 2013 Jan 15

PMID : 23122841






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Loss of O6-methylguanine-DNA methyltransferase confers collateral sensitivity to carmustine in topoisomerase II-mediated doxorubicin resistant triple negative breast cancer cells. Carmustine O-6-methylguanine-DNA methyltransferase Homo sapiens
2 The collateral sensitivity of CALDOX cells to carmustine provides the rationale to evaluate MGMT promoter methylation status to design better therapeutic strategies for triple negative breast cancer. Carmustine O-6-methylguanine-DNA methyltransferase Homo sapiens