Title : Association between single nucleotide polymorphisms (SNPs) and toxicity of advanced non-small-cell lung cancer patients treated with chemotherapy.

Pub. Date : 2012

PMID : 23118991






1 Functional Relationships(s)
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1 In this study, we assessed whether polymorphisms in genes of nucleotide excision repair (NER) pathway, including ERCC5, ERCC6, MMS19L, CCNH, XPC, RRM1, can affect the tolerability of platinum-based chemotherapy in NSCLC patients. Platinum ERCC excision repair 5, endonuclease Homo sapiens