Title : Clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"): the influence of gender and genetics (CYP2D6, COMT, 5-HTT).

Pub. Date : 2012

PMID : 23112822






6 Functional Relationships(s)
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1 UNLABELLED: The synthetic psychostimulant MDMA (+- 3,4-methylenedioxymethamphetamine, ecstasy) acts as an indirect serotonin, dopamine, and norepinephrine agonist and as a mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6). N-Methyl-3,4-methylenedioxyamphetamine cytochrome P450 family 2 subfamily D member 6 Homo sapiens
2 UNLABELLED: The synthetic psychostimulant MDMA (+- 3,4-methylenedioxymethamphetamine, ecstasy) acts as an indirect serotonin, dopamine, and norepinephrine agonist and as a mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6). N-Methyl-3,4-methylenedioxyamphetamine cytochrome P450 family 2 subfamily D member 6 Homo sapiens
3 UNLABELLED: The synthetic psychostimulant MDMA (+- 3,4-methylenedioxymethamphetamine, ecstasy) acts as an indirect serotonin, dopamine, and norepinephrine agonist and as a mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6). N-Methyl-3,4-methylenedioxyamphetamine cytochrome P450 family 2 subfamily D member 6 Homo sapiens
4 UNLABELLED: The synthetic psychostimulant MDMA (+- 3,4-methylenedioxymethamphetamine, ecstasy) acts as an indirect serotonin, dopamine, and norepinephrine agonist and as a mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6). N-Methyl-3,4-methylenedioxyamphetamine cytochrome P450 family 2 subfamily D member 6 Homo sapiens
5 UNLABELLED: The synthetic psychostimulant MDMA (+- 3,4-methylenedioxymethamphetamine, ecstasy) acts as an indirect serotonin, dopamine, and norepinephrine agonist and as a mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6). N-Methyl-3,4-methylenedioxyamphetamine cytochrome P450 family 2 subfamily D member 6 Homo sapiens
6 UNLABELLED: The synthetic psychostimulant MDMA (+- 3,4-methylenedioxymethamphetamine, ecstasy) acts as an indirect serotonin, dopamine, and norepinephrine agonist and as a mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6). N-Methyl-3,4-methylenedioxyamphetamine cytochrome P450 family 2 subfamily D member 6 Homo sapiens