Title : Phosphorylation of p68 RNA helicase by p38 MAP kinase contributes to colon cancer cells apoptosis induced by oxaliplatin.

Pub. Date : 2012 Oct 31

PMID : 23110695






3 Functional Relationships(s)
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1 Phosphorylation of p68 RNA helicase by p38 MAP kinase contributes to colon cancer cells apoptosis induced by oxaliplatin. Oxaliplatin DEAD-box helicase 5 Homo sapiens
2 RESULTS: In this report, we characterized the role of p68 phosphorylation in apoptosis induction under the treatment of oxaliplatin in the colon cancer cells. Oxaliplatin DEAD-box helicase 5 Homo sapiens
3 Our data suggest that oxaliplatin treatment activates p38 MAP kinase, which subsequently phosphorylates p68 at T564 and/or T446. Oxaliplatin DEAD-box helicase 5 Homo sapiens