Pub. Date : 2012
PMID : 23109869
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effects of sorafenib on C-terminally truncated androgen receptor variants in human prostate cancer cells. | Sorafenib | androgen receptor | Homo sapiens |
| 2 | In this study we demonstrate that the multikinase inhibitor sorafenib inhibits AR as well as ARDeltaLBD-signalling in CRPCa cells. | Sorafenib | androgen receptor | Homo sapiens |
| 3 | In line with these observations, maximal antiproliferative effects of sorafenib were achieved in AR and ARDeltaLBD-positive PCa cells. | Sorafenib | androgen receptor | Homo sapiens |
| 4 | The present findings warrant further investigations on sorafenib as an option for the treatment of advanced AR-positive PCa. | Sorafenib | androgen receptor | Homo sapiens |