Pub. Date : 1990 Feb
PMID : 2309931
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Neuropeptide Y in the hypothalamus: effect on corticosterone and single-unit activity. | Corticosterone | neuropeptide Y | Rattus norvegicus |
| 2 | The purpose of the present study was to determine whether neuropeptide Y (NPY) acts within the hypothalamic paraventricular nucleus (PVN) or the suprachiasmatic nucleus (SCN) to alter circulating levels of corticosterone and to evaluate the effects of NPY on the single-unit response of PVN and SCN neurons using the hypothalamic slice preparation. | Corticosterone | neuropeptide Y | Rattus norvegicus |
| 3 | The purpose of the present study was to determine whether neuropeptide Y (NPY) acts within the hypothalamic paraventricular nucleus (PVN) or the suprachiasmatic nucleus (SCN) to alter circulating levels of corticosterone and to evaluate the effects of NPY on the single-unit response of PVN and SCN neurons using the hypothalamic slice preparation. | Corticosterone | neuropeptide Y | Rattus norvegicus |
| 4 | NPY injected into the PVN 4 h after light onset resulted in corticosterone levels of 13.15 +/- 2.18 (SE) micrograms/dl within 1 h, which were significantly higher than the corticosterone levels of 4.08 +/- 1.78 micrograms/dl seen in rats receiving Sal injections. | Corticosterone | neuropeptide Y | Rattus norvegicus |
| 5 | In summary, NPY alters the electrical activity of both SCN and PVN neurons but appears to act only within the PVN to influence circulating levels of corticosterone. | Corticosterone | neuropeptide Y | Rattus norvegicus |