Title : Quantitative change of IgA hinge O-glycan composition is a novel marker of therapeutic responses of IgA nephropathy.

Pub. Date : 2012 Nov 23

PMID : 23098908






2 Functional Relationships(s)
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1 In the present study, the molar ratios of GalNAc or Gal to HP were analyzed for serum IgA from IgAN patients. N-acetylgalactosaminuronic acid IGAN1 Homo sapiens
2 The GalNAc/HP ratio was increased in the patients who achieved remission after a combination therapy of tonsillectomy and intravenous corticosteroid, suggesting any non-innate factors to affect the IgA O-glycosylation in IgAN that is thought to be inherently determined. N-acetylgalactosaminuronic acid IGAN1 Homo sapiens