Pub. Date : 2013 Jan
PMID : 23098818
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The catalytic competence of cytochrome P450 in the synthesis of serotonin from 5-methoxytryptamine in the brain: an in vitro study. | 5-Methoxytryptamine | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |
| 2 | The aim of present study was to identify rat cytochrome P450 (CYP) isoforms which can catalyze the O-demethylation of 5-methoxytryptamine to serotonin, and to find out whether that alternative pathway of serotonin synthesis may take place in the brain. | 5-Methoxytryptamine | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |
| 3 | The aim of present study was to identify rat cytochrome P450 (CYP) isoforms which can catalyze the O-demethylation of 5-methoxytryptamine to serotonin, and to find out whether that alternative pathway of serotonin synthesis may take place in the brain. | 5-Methoxytryptamine | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |
| 4 | Of the rat CYP isoforms studied, CYP2D isoforms were the most efficient in catalyzing the O-demethylation of 5-methoxytryptamine to serotonin, but they were less effective than the human isoform CYP2D6. | 5-Methoxytryptamine | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |