Title : Transcriptional regulation of RKIP expression by androgen in prostate cells.

Pub. Date : 2012

PMID : 23095933






5 Functional Relationships(s)
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1 METHODS: The effect of dihydrotestosterone (DHT) on RKIP expression in normal prostate epithelial cells was determined by real-time RT-PCR and Western blot. Dihydrotestosterone phosphatidylethanolamine binding protein 1 Mus musculus
2 METHODS: The effect of dihydrotestosterone (DHT) on RKIP expression in normal prostate epithelial cells was determined by real-time RT-PCR and Western blot. Dihydrotestosterone phosphatidylethanolamine binding protein 1 Mus musculus
3 RESULTS: Here we report that DHT positively regulates the transcription of RKIP in the normal prostate epithelial cells. Dihydrotestosterone phosphatidylethanolamine binding protein 1 Mus musculus
4 Transfection of the cells with a RKIP promoter-driven luciferase reporter vector showed that DHT increased RKIP promoter activity in parallel with changes in expression. Dihydrotestosterone phosphatidylethanolamine binding protein 1 Mus musculus
5 Transfection of the cells with a RKIP promoter-driven luciferase reporter vector showed that DHT increased RKIP promoter activity in parallel with changes in expression. Dihydrotestosterone phosphatidylethanolamine binding protein 1 Mus musculus