Title : Global protein conjugation by ubiquitin-like-modifiers during ischemic stress is regulated by microRNAs and confers robust tolerance to ischemia.

Pub. Date : 2012

PMID : 23094087






1 Functional Relationships(s)
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1 We have also shown that overexpression of Ubc9, SUMO-1, or SUMO-2/3 provides protection against ischemic damage in cell lines and cortical neurons exposed to oxygen/glucose deprivation, and in mice exposed to middle cerebral artery occlusion. Oxygen small ubiquitin-like modifier 2 Mus musculus