Title : Evidence of cell damage induced by major components of a diet-compatible mixture of oxysterols in human colon cancer CaCo-2 cell line.

Pub. Date : 2013 Mar

PMID : 23092829






1 Functional Relationships(s)
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1 Sixty muM oxysterol mixture showed a slight pro-apoptotic effect on human colon cancer CaCo-2 cell line, evaluated in terms of caspase-3 and caspase-7 activation; conversely, 7alpha-hydroxycholesterol, 7beta-hydroxycholesterol and 5alpha,6alpha-epoxycholesterol were identified to be able to induce a significant pro-apoptotic effect if added to cell culture singly; 7beta-hydroxycholesterol had stronger action than other compounds. Oxysterols caspase 3 Homo sapiens