Title : R- and S-equol have equivalent cytoprotective effects in Friedreich's ataxia.

Pub. Date : 2012 Oct 22

PMID : 23088310






1 Functional Relationships(s)
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1 Using L-buthionine (S,R)-sulfoximine (BSO) to induce oxidative stress in human FRDA fibroblasts, we determine the potency and efficacy of the soy-derived ERbeta agonist S-equol and its ERalpha-preferring enantiomer, R-equol in vitro on cell viability and ROS accumulation. Equol estrogen receptor 1 Homo sapiens