Title : Sirtuin7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors MiR-125a-5p and MiR-125b.

Pub. Date : 2013 Mar

PMID : 23079745






1 Functional Relationships(s)
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1 Furthermore, treatment of HCC cells with 5-aza-2"-deoxycytidine or ectopic expression of wildtype but not mutated p53 restored miR-125a-5p and miR-125b expression and inhibited tumor cell growth, suggesting their regulation by promoter methylation and p53 activity. Decitabine tumor protein p53 Homo sapiens