Title : HCV NS5A protein containing potential ligands for both Src homology 2 and 3 domains enhances autophosphorylation of Src family kinase Fyn in B cells.

Pub. Date : 2012

PMID : 23077515






2 Functional Relationships(s)
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1 These results suggest that NS5A directly binds to the SH2 domain of Fyn in a tyrosine phosphorylation-dependent manner. Tyrosine FYN proto-oncogene, Src family tyrosine kinase Homo sapiens
2 Lastly, we showed that the expression of NS5A in B cells increased phosphorylation of activation loop tyrosine in the kinase domain of Fyn. Tyrosine FYN proto-oncogene, Src family tyrosine kinase Homo sapiens