Pub. Date : 2012 Oct 15
PMID : 23067370
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: HIV infection results in inhibited cholesterol efflux by apolipoprotein A-I (apoA-I) in macrophages, and this impairment involves Nef mediated down-regulation and redistribution of ATP-binding cassette transporter A1 (ABCA-1). | Cholesterol | S100 calcium binding protein B | Homo sapiens |
| 2 | RESULTS: Our results reveal that Cav-1 restores the Nef -mediated impairment of cholesterol efflux by apoA-I in both cell types. | Cholesterol | S100 calcium binding protein B | Homo sapiens |
| 3 | CONCLUSIONS: These observations suggest that the interplay of Cav-1 with Nef and cholesterol subsequently counters Nef induced impairment of cholesterol efflux by apoA-l. | Cholesterol | S100 calcium binding protein B | Homo sapiens |
| 4 | CONCLUSIONS: These observations suggest that the interplay of Cav-1 with Nef and cholesterol subsequently counters Nef induced impairment of cholesterol efflux by apoA-l. | Cholesterol | S100 calcium binding protein B | Homo sapiens |
| 5 | CONCLUSIONS: These observations suggest that the interplay of Cav-1 with Nef and cholesterol subsequently counters Nef induced impairment of cholesterol efflux by apoA-l. | Cholesterol | S100 calcium binding protein B | Homo sapiens |