Title : Pregnane glycosides interfere with steroidogenic enzymes to down-regulate corticosteroid production in human adrenocortical H295R cells.

Pub. Date : 2013 May

PMID : 23065845






1 Functional Relationships(s)
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1 At the same time, pregnane glycosides had no effect on the CYP1, 2, or 3 drug and steroid metabolism enzymes and showed weak Na(+) /K(+) ATPase and glucocorticoid receptor binding. pregnane glycoside nuclear receptor subfamily 3 group C member 1 Homo sapiens