Title : Green tea epigallocatechin-3-gallate modulates differentiation of naïve CD4⁺ T cells into specific lineage effector cells.

Pub. Date : 2013 Apr

PMID : 23064699






3 Functional Relationships(s)
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1 These effects, in turn, may be mediated by EGCG-induced downregulation of transducers p-STAT1 and p-STAT4 for Th1, and p-STAT3 for Th17. epigallocatechin gallate signal transducer and activator of transcription 3 Mus musculus
2 EGCG-induced change in Th17/Treg balance may be mediated by its inhibition of IL-6 signaling because EGCG inhibited soluble IL-6R, membrane gp130, and IL-6-induced phosphorylation of STAT3. epigallocatechin gallate signal transducer and activator of transcription 3 Mus musculus
3 EGCG-induced change in Th17/Treg balance may be mediated by its inhibition of IL-6 signaling because EGCG inhibited soluble IL-6R, membrane gp130, and IL-6-induced phosphorylation of STAT3. epigallocatechin gallate signal transducer and activator of transcription 3 Mus musculus