Title : Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of resting human T cells.

Pub. Date : 2012 Nov 1

PMID : 23058634






1 Functional Relationships(s)
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Protein Name
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1 Pretreatment of resting T cells with KU 55933 blocked phosphorylation of ATM, H2AX and p53, which, in turn, prevented PUMA expression, caspase activation and apoptosis. 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one H2A.X variant histone Homo sapiens