Title : Effects of nuclear receptor transactivation on boar taint metabolism and gene expression in porcine hepatocytes.

Pub. Date : 2013 Jan

PMID : 23032374






1 Functional Relationships(s)
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1 FXR had the greatest effect on 3MI metabolism, increasing the expression of CYP2E1 by 1.29-fold and increasing the production of the key metabolite 6-hydroxy-3-methylindole (6-OH-3MI), while decreasing 5-hydroxy-3-methylindole (5-OH-3MI) production. Skatole nuclear receptor subfamily 1 group H member 4 Homo sapiens