Title : Isoorientin induces apoptosis through mitochondrial dysfunction and inhibition of PI3K/Akt signaling pathway in HepG2 cancer cells.

Pub. Date : 2012 Nov 15

PMID : 23026832






1 Functional Relationships(s)
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1 Furthermore, the addition of a ROS inhibitor (N-acetyl cysteine, NAC) or iNOS inhibitor (N-[3-(aminomethyl) benzyl] acetamidine, dihydrochloride, 1400W) significantly diminished the apoptosis induced by ISO and also blocked the phosphorylation of Akt. N-(3-(aminomethyl)benzyl)acetamidine AKT serine/threonine kinase 1 Homo sapiens