Pub. Date : 2012 Nov
PMID : 23022044
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Thioridazine suppressed phosphorylation of the signaling regulators downstream of the focal adhesion kinase (FAK) through alphavbeta3 integrin, which also include Akt, phosphoinositide-dependent protein kinase 1 (PDK-1), mammalian target of rapamycin (mTOR), ribosomal protein S6 kinase (p70S6K), but had no effect on VEGF-stimulated extracellular signal-regulated kinase (ERK) phosphorylation. | Thioridazine | AKT serine/threonine kinase 1 | Homo sapiens |