Title : Aquaporin 3 (AQP3) participates in the cytotoxic response to nucleoside-derived drugs.

Pub. Date : 2012 Sep 27

PMID : 23017148






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 BACKGROUND: Nucleoside analogs used in the chemotherapy of solid tumors, such as the capecitabine catabolite 5"-deoxy-5-fluorouridine (5"-DFUR) trigger a transcriptomic response that involves the aquaglyceroporin aquaporin 3 along with other p53-dependent genes. Nucleosides tumor protein p53 Homo sapiens