Title : Reduction of furan derivatives by overexpressing NADH-dependent Adh1 improves ethanol fermentation using xylose as sole carbon source with Saccharomyces cerevisiae harboring XR-XDH pathway.

Pub. Date : 2013 Mar

PMID : 23001007






2 Functional Relationships(s)
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1 In addition, we found that overexpression of wild-type ADH1 prevented the more severe inhibitory effects of furfural in xylose fermentation as well as overexpression of TMB3000-derived mutant. Furaldehyde alcohol dehydrogenase ADH1 Saccharomyces cerevisiae S288C
2 After 120 h of fermentation, the recombinant strains overexpressing wild-type and mutant ADH1 completely consumed 50 g/L xylose in the presence of 40 mM furfural and most efficiently produced ethanol (15.70 g/L and 15.24 g/L) when compared with any other test conditions. Furaldehyde alcohol dehydrogenase ADH1 Saccharomyces cerevisiae S288C