Title : Divalent metal transporter 1 regulates iron-mediated ROS and pancreatic β cell fate in response to cytokines.

Pub. Date : 2012 Oct 3

PMID : 23000401






1 Functional Relationships(s)
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1 Through a combination of in vitro and in vivo studies, we show that the proinflammatory cytokine IL-1beta induces divalent metal transporter 1 (DMT1) expression correlating with increased beta cell iron content and ROS production. Reactive Oxygen Species interleukin 1 beta Mus musculus