Title : Novel amide- and sulfonamide-based aromatic ethanolamines: effects of various substituents on the inhibition of acid and neutral ceramidases.

Pub. Date : 2012 Oct 15

PMID : 22989912






1 Functional Relationships(s)
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1 However, the hydrophobicity and the steric effects of longer alkyl chains (n-Pr, n-Bu or t-Bu groups) at the phenyl ring were found to be important for an enhanced selectivity towards aCDase over nCDase. Busulfan N-acylsphingosine amidohydrolase 2 Homo sapiens