Title : Vitamin D metabolism and action in human marrow stromal cells: effects of chronic kidney disease.

Pub. Date : 2013 Jul

PMID : 22989482






1 Functional Relationships(s)
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1 Human marrow stromal cells (hMSCs) are targets of 1alpha,25-dihydroxyvitamin D [1alpha,25(OH)2D3] action to promote their differentiation to osteoblasts, but they also participate in vitamin D metabolism by converting 25-dihydroxyvitamin D3 [25(OH)D3] to 1alpha,25(OH)2D3 by 1alpha-hydroxylase (CYP27B1). 1,25-dihydroxyvitamin D cytochrome P450 family 27 subfamily B member 1 Homo sapiens