Pub. Date : 2013 Jul 25
PMID : 22986523
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cells lacking E6AP expression have reduced capacity to accumulate ROS, and oxidative DNA damage, in response to 20% cell culture oxygen levels, treatment with hydrogen peroxide and expression of oncogenic RAS. | Hydrogen Peroxide | ubiquitin protein ligase E3A | Homo sapiens |
| 2 | In a xenograft model, downregulation of E6AP renders transplanted tumours refractory to growth-suppressive effects of hydrogen peroxide. | Hydrogen Peroxide | ubiquitin protein ligase E3A | Homo sapiens |