Title : Memory maintenance by PKMζ--an evolutionary perspective.

Pub. Date : 2012 Sep 18

PMID : 22986281






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The persistent activity of the autonomously active, atypical protein kinase C (aPKC) isoform, PKMzeta, is both necessary and sufficient for maintaining LTP. pkmzeta atypical protein kinase C Drosophila melanogaster
2 The persistent activity of the autonomously active, atypical protein kinase C (aPKC) isoform, PKMzeta, is both necessary and sufficient for maintaining LTP. pkmzeta atypical protein kinase C Drosophila melanogaster
3 PKMzeta persistently enhances synaptic strength by maintaining increased numbers of AMPA receptors at postsynaptic sites, a mechanism that might have evolved from the general function of aPKC in trafficking membrane proteins to the apical compartment of polarized cells. pkmzeta atypical protein kinase C Drosophila melanogaster