Pub. Date : 1990 Feb
PMID : 2298157
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Testosterone at high concentrations interacts with the human androgen receptor similarly to dihydrotestosterone. | Testosterone | androgen receptor | Homo sapiens |
| 2 | In up-regulation experiments, 2 nM [3H]testosterone produced a 34% increase in specific androgen receptor binding after 24 h, whereas 20 nM [3H]testosterone produced an average increase of 64%. | Testosterone | androgen receptor | Homo sapiens |
| 3 | Our results suggest that the weaker androgenic potency of testosterone compared to that of dihydrotestosterone resides in its weaker interaction with the androgen receptor, most clearly demonstrable as an increase in the dissociation rate of testosterone from the receptor. | Testosterone | androgen receptor | Homo sapiens |
| 4 | Our results suggest that the weaker androgenic potency of testosterone compared to that of dihydrotestosterone resides in its weaker interaction with the androgen receptor, most clearly demonstrable as an increase in the dissociation rate of testosterone from the receptor. | Testosterone | androgen receptor | Homo sapiens |