Title : Effects of geissoschizine methyl ether, an indole alkaloid in Uncaria hook, a constituent of yokukansan, on human recombinant serotonin 7 receptor.

Pub. Date : 2013 Jan

PMID : 22968712






1 Functional Relationships(s)
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1 A competitive binding assay using CHO membranes showed that GM (IC(50) = 0.034 muM) more strongly inhibited the binding of the radioligand [(3)H] LSD to 5-HT(7) receptor than the other alkaloids, suggesting that GM is bound to 5-HT(7) receptor. Alkaloids latexin Homo sapiens