Title : Specificity of IgE antibodies from patients allergic to goat's milk and tolerant to cow's milk determined with plasmin-derived peptides of bovine and caprine β-caseins.

Pub. Date : 2012 Oct

PMID : 22961864






2 Functional Relationships(s)
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Protein Name
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1 By using synthetic peptides, the immunodominant IgE-binding epitope recognized by most GM-allergic/CM-tolerant patients was located in the caprine domain 49-79. gm immunoglobulin heavy constant epsilon Homo sapiens
2 CONCLUSION: The restricted specificity of the IgE response toward the caprine beta-CN in GM-allergic/CM-tolerant patients is mainly directed against the domain 49-79, which differs from its bovine counterpart by only three amino acid substitutions. gm immunoglobulin heavy constant epsilon Homo sapiens