Title : CD14(+)S100A9(+) monocytic myeloid-derived suppressor cells and their clinical relevance in non-small cell lung cancer.

Pub. Date : 2012 Nov 15

PMID : 22955317






1 Functional Relationships(s)
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1 Isolated CD11b(+)CD14(+) cells suppressed CD8(+) T-cell proliferation and IFN-gamma production, and the former effect was attenuated by the inducible nitric oxide synthase (iNOS) inhibitor aminoguanidine hydrochloride, arginase inhibitor N-hydroxy-nor-l-arginine (nor-NOHA), and blocking antibodies for IL-4Ralpha(+) and IL-10. pimagedine CD8a molecule Homo sapiens