Title : Increased expression levels of WAVE3 are associated with the progression and metastasis of triple negative breast cancer.

Pub. Date : 2012

PMID : 22952619






1 Functional Relationships(s)
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1 We have identified the WAVE3 protein, which is a critical regulator of actin cytoskeleton dynamics that are required for the motility and invasion of cancer cells through its activation of the Arp2/3 complex, as a key regulator of the different steps of the invasion-metastasis cascade in BC, especially in the more aggressive TNBCs. tnbcs actin related protein 2 Homo sapiens