Title : CAPE suppresses VEGFR-2 activation, and tumor neovascularization and growth.

Pub. Date : 2013 Feb

PMID : 22935775






1 Functional Relationships(s)
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1 Here, we show that CAPE suppressed VEGF-induced proliferation, tube formation, migration, the formation of actin stress fibers and loss of VE-cadherin at cell-cell contacts in endothelial cells, indicating the inhibition of VEGF-mediated VEGF receptor-2 (VEGFR-2) and its downstream signal activation in vitro. caffeic acid phenethyl ester cadherin 5 Mus musculus