Title : Cross-priming for antitumor CTL induced by soluble Ag + polyI:C depends on the TICAM-1 pathway in mouse CD11c(+)/CD8α(+) dendritic cells.

Pub. Date : 2012 Aug 1

PMID : 22934250






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cross-priming for antitumor CTL induced by soluble Ag + polyI:C depends on the TICAM-1 pathway in mouse CD11c(+)/CD8alpha(+) dendritic cells. Poly I-C toll-like receptor adaptor molecule 1 Mus musculus
2 Endosomal TLR3 and cytoplasmic RIG-I/MDA5 are reportedly responsible for polyI:C sensing and presumed to deliver signal for cross-presentation via TICAM-1 (TRIF) and IPS-1 (MAVS, Cardif, VISA) adaptors, respectively. Poly I-C toll-like receptor adaptor molecule 1 Mus musculus