Title : Prostaglandin E(2) mediates proliferation and chloride secretion in ADPKD cystic renal epithelia.

Pub. Date : 2012 Nov 15

PMID : 22933297






1 Functional Relationships(s)
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1 PGE(2) and EP4 receptor agonism (TCS 2510) increased intracellular cAMP concentration and the abundance of active beta-catenin in PC-1-deficient cells, suggesting a mechanism for PGE(2)-mediated proliferation. Cyclic AMP prostaglandin E receptor 4 Homo sapiens