CPRiL

4 Functional Relationships(s) Download
	Sentence	Compound Name	Protein Name	Organism
1	To better understand the mechanisms that determine the response to PARP inhibitors, we investigated whether enzymes involved in metabolism of the PARP substrate, beta-NAD(+) , might alter the response to a clinical PARP inhibitor.	NAD	collagen type XI alpha 2 chain	Homo sapiens
2	To better understand the mechanisms that determine the response to PARP inhibitors, we investigated whether enzymes involved in metabolism of the PARP substrate, beta-NAD(+) , might alter the response to a clinical PARP inhibitor.	NAD	collagen type XI alpha 2 chain	Homo sapiens
3	NAMPT is a rate-limiting enzyme involved in the generation of the PARP substrate beta-NAD(+) and the suppression of beta-NAD(+) levels by NAMPT inhibition most likely explains these observations.	NAD	collagen type XI alpha 2 chain	Homo sapiens
4	NAMPT is a rate-limiting enzyme involved in the generation of the PARP substrate beta-NAD(+) and the suppression of beta-NAD(+) levels by NAMPT inhibition most likely explains these observations.	NAD	collagen type XI alpha 2 chain	Homo sapiens