Pub. Date : 2012 Sep
PMID : 22926964
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ACC1 overexpression led to decreased fatty acid content in the squalene-overproducing strain (factor of 0.7), while sterols and squalene were increased (factor of 1.5). | Fatty Acids | acetyl-CoA carboxylase ACC1 | Saccharomyces cerevisiae S288C |
| 2 | In the wild-type strain, ACC1 overexpression led to increased levels of both fatty acids and squalene/sterols (factors of 4.0 and 1.7, respectively). | Fatty Acids | acetyl-CoA carboxylase ACC1 | Saccharomyces cerevisiae S288C |
| 3 | The microarray expression profiles showed that genes upregulated in ACC1-overexpressing strains are FAS1, ERG11, ERG28, ERG5, ERG2 and ERG20, supporting the observed increase of zymosterol and saturated fatty acids. | Fatty Acids | acetyl-CoA carboxylase ACC1 | Saccharomyces cerevisiae S288C |