Title : Radiosensitizing effects of arsenic trioxide on MCF-7 human breast cancer cells exposed to 89 strontium chloride.

Pub. Date : 2012 Nov

PMID : 22922982






2 Functional Relationships(s)
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1 Since expression of Bax was unchanged following treatment, As2O3 effectively reduced the Bcl-2/Bax ratio. Arsenic Trioxide BCL2 associated X, apoptosis regulator Homo sapiens
2 As2O3 (1-2 microM) enhances the cytotoxic effects of 89SrCl2 on the MCF-7 human breast cancer cell line by inducing G2 phase delay and promoting apoptosis through the reduction of the Bcl-2/Bax ratio. Arsenic Trioxide BCL2 associated X, apoptosis regulator Homo sapiens