Title : Inflammatory prostaglandin E2 signaling in a mouse model of Alzheimer disease.

Pub. Date : 2012 Nov

PMID : 22915243






2 Functional Relationships(s)
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1 INTERPRETATION: Our findings identify the PGE(2) EP3 receptor as a novel proinflammatory, proamyloidogenic, and synaptotoxic signaling pathway, and suggest a role for COX-PGE(2) -EP3 signaling in the development of AD. Dinoprostone prostaglandin E receptor 3 (subtype EP3) Mus musculus
2 INTERPRETATION: Our findings identify the PGE(2) EP3 receptor as a novel proinflammatory, proamyloidogenic, and synaptotoxic signaling pathway, and suggest a role for COX-PGE(2) -EP3 signaling in the development of AD. Dinoprostone prostaglandin E receptor 3 (subtype EP3) Mus musculus