Pub. Date : 2012
PMID : 22912749
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cystinosis is a rare disease caused by homozygous mutations of the CTNS gene, encoding a cystine efflux channel in the lysosomal membrane. | Cystine | cystinosin, lysosomal cystine transporter | Homo sapiens |
| 2 | Here we show that human mesenchymal stem cells, from amniotic fluid or bone marrow, reduce pathologic cystine accumulation in co-cultured CTNS mutant fibroblasts or proximal tubular cells from cystinosis patients. | Cystine | cystinosin, lysosomal cystine transporter | Homo sapiens |