Title : Influence of iron regulation on the metabolome of Cryptococcus neoformans.

Pub. Date : 2012

PMID : 22911836






1 Functional Relationships(s)
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1 Our metabolite analysis revealed that Cir1 influences the glycolytic pathway, ergosterol biosynthesis and inositol metabolism, which require numerous iron-dependent enzymes and play important roles in pathogenesis and antifungal sensitivity of the fungus. Inositol corepressor interacting with RBPJ, CIR1 Homo sapiens